Multisizer 4e Coulter Counter

The required Multisizer provides improved functionality and analysis capabilities, in addition to allowing continued measurement of cell size, counts, and distribution using the Coulter method across multiple clinical research study protocols. 

                                                  Specifications & Requirements

                        The product shall include/use: 

• Coulter method of measurement using patented digital pulse processing technology 

• Automatic aperture blockage detection and clearing during runs and sample analysis 

• Code scanner to scan bar codes on samples, electrolytes, aperture tubes, and sample beakers 

• Fluid level monitoring for solutions and waste 

• Selectable stirrer speed and direction 

• Particle sizing range: 0.2 – 1,600uM 

• Measurement range: 2 – 80% of aperture size 

• Measurement linearity: Diameter ± 1%, Volume ± 3% 

• Dynamic range (accuracy): 1:40 (diameter), 1:64,000 (volume) 

• Accurate determination of sample cell number, size, distribution, and concentration 

• Particle count, sizing, and volume distribution data, including diameter, volume, and area of number, number percent, number per mL, volume, volume percent, volume per mL, surface area, surface area percent, surface area per mL 

• Pulse distribution data, including time, sequence and width for pulse height diameter, pulse height volume, pulse height volt, pulse width, pulse area, average pulse height diameter, average pulse height volume and average pulse width. Number distribution by width. 

• Up to 400 size classes or channels with the ability to change number of size classes or channels and width and reprocess as needed without having to re-run the samples 

• Time-stamped pulses up to 525,000 per single analysis 

• Modes for Total Count (up to 500,000 counts), Modal Count (up to 100,000 counts), and Volumetric Count (up to 2000uL) 

• Digital Pulse Processor with proprietary high-speed signal digitalization 

• Real time detection of volume changes 

• Stirrer with ability to adjust stir speed and direction for even particle distribution in sample suspensions 

• 100uM and 400uM size aperture tubes, with instrument ability to use apertures ranging from 10uM up to 2000uM size as needed, with aperture tube calibration and verification 

• 100/200mL beakers, with ability to use additional size beakers and accuvettes, as required by the sample type, sample volume, or other need 

• Isoton II Diluent and Coulter Clenz solutions for instrument operation and cleaning, and spigot assemblies for both solutions 

• Mixed Standards Kit (L2, L5, L10, L20, L40) 

• 300uM Particle Standard 

• Installation